该研究方向的主要发表论文如下:
1. Meng, H.; Xing, G.; Blanco, E.; Song, Y.; Zhao, L.; Sun, B.; Li, X.; Wang, P. C.; Korotcov, A.; Li, W.; Liang, X.-J.; Chen, C.; Yuan, H.; Zhao, F.; Chen, Z.; Sun, T.; Chai, Z.; Ferrari, M.; Zhao, Y., Gadolinium metallofullerenol nanoparticles inhibit cancer metastasis through matrix metalloproteinase inhibition: imprisoning instead of poisoning cancer cells. Nanomedicine: Nanotechnology, Biology and Medicine 2012, 8 (2), 136-146.
2. Wu, Y.; Jiao, F.; Han, S.; Fan, T.; Liu, Y.; Li, W.; Hu, L.; Zhao, Y.; Chen, C., Construction of amphiphilic copolymer nanoparticles based on hyperbranched Poly (Amine-Ester) and 1,2-Dipalmitoyl-Sn-Glycero-3-Phosphoethanolamine as drug carriers for cancer therapy. Nanomedicine : nanotechnology, biology, and medicine 2011, 7 (6), 945-54.
3. Yu, C.; Hu, Y.; Duan, J.; Yuan, W.; Wang, C.; Xu, H.; Yang, X.-D., Novel Aptamer-Nanoparticle Bioconjugates Enhances Delivery of Anticancer Drug to MUC1-Positive Cancer Cells In Vitro. Plos One 2011, 6 (9).
4. Wang, T.; Zhang, C.; Liang, X.-J.; Liang, W.; Wu, Y., Hydroxypropyl-beta-Cyclodextrin Copolymers and Their Nanoparticles as Doxorubicin Delivery System. Journal of Pharmaceutical Sciences 2011, 100 (3), 1067-1079.
5. Wang, L. M.; Liu, Y.; Li, W.; Jiang, X. M.; Ji, Y. L.; Wu, X. C.; Xu, L. G.; Qiu, Y.; Zhao, K.; Wei, T. T.; Li, Y. F.; Zhao, Y. L.; Chen, C. Y., Selective Targeting of Gold Nanorods at the Mitochondria of Cancer Cells: Implications for Cancer Therapy. Nano Lett. 2011, 11 (2), 772-780
6. Wang, H.; Zhao, Y.; Wu, Y.; Hu, Y.-L.; Nan, K.; Nie, G.; Chen, H., Enhanced anti-tumor efficacy by co-delivery of doxorubicin and paclitaxel with amphiphilic methoxy PEG-PLGA copolymer nanoparticles. Biomaterials 2011, 32 (32), 8281-8290.
7. Sun, C.; Yang, H.; Yuan, Y.; Tian, X.; Wang, L. M.; Guo, Y.; Xu, L.; Lei, J. L.; Gao, N.; Anderson, G. J.; Liang, X. J.; Chen, C. Y.; Zhao, Y. L.; Nie, G. J., Controlling Assembly of Paired Gold Clusters within Apoferritin Nanoreactor for in Vivo Kidney Targeting and Biomedical Imaging. J. Am. Chem. Soc. 2011, 133, 8617-8624.
8. Schneider, J. A.; Grodzinski, P.; Liang, X. J., Cancer nanotechnology research in the United States and China: cooperation to promote innovation. Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology 2011, 3 (5), 441-448.
9. Meng, J.; Xing, J.; Wang, Y.; Lu, J.; Zhao, Y.; Gao, X.; Wang, P. C.; Jia, L.; Liang, X., Epigenetic modulation of human breast cancer by metallofullerenol nanoparticles: in vivo treatment and in vitro analysis. Nanoscale 2011, DOI: 10.1039/c1nr10898k.
10. Ma, X. W.; Zhao, Y. L.; Liang, X. J., Nanodiamond delivery circumvents tumor resistance to doxorubicin. Acta Pharmacologica Sinica 2011, 32, 543-544.
11. Ma, X. W.; Zhao, Y. L.; Liang, X. J., Theranostic Nanoparticles Engineered for Clinic and Pharmaceutics. Accounts of Chemical Research 2011, DOI:10.1021/ar2000056.
12. Kumar, A.; Boruah, B. M.; Liang, X. J., Gold Nanoparticles: Promising Nanomaterials for the Diagnosis of Cancer and HIV/AIDS. Journal of Nanomaterials 2011, 2011, 001-017.
13. Fan, T.; Li, M.; Wu, X.; Li, M.; Wu, Y., Preparation of thermoresponsive and pH-sensitivity polymer magnetic hydrogel nanospheres as anticancer drug carriers. Colloids and Surfaces B-Biointerfaces 2011, 88 (2), 593-600.
14. Zhou, G. Q.; Li, Y. F.; Liu, Y.; Ge, C. C.; Li, W.; Sun, B. Y.; Li, B.; Gao, Y. X.; Chen, C. Y., Subcellular Distribution of Polyhydroxylated Metallofullerene Gd@C82 (OH)22 in Different Tissues of Tumor-Bearing Mice. J. Nanosci. Nanotechnol. 2010, 10(12), 8597-8602(6).
15. Xue, X.; You, S.; Liang, X. J., Chemotherapeutic resistance of cancer and its related gene therapeutic drugs. Chinese Journal of Medicinal Chemistry 2010, 20 (5), 460-466.
16. Wang, Y. Z.; Lv, J.; Ma, X. W.; Wang, D. L.; Ma, H. L.; Chang, Y. Z.; Nie, G. J.; Jia, L.; Duan, X. L.; Liang, X. J., Specific Hemosiderin Deposition in Spleen Induced by a Low Dose of Cisplatin: Altered Iron Metabolism and Its Implication as an Acute Hemosiderin Formation Model. Current Drug Metabolism 2010, 11, 507-515.
17. Wang, T. W.; Wu, Y.; Zeng, A. J., Synthesis and Characterization of Amphiphilic Pluronic (F68)-1,2-dipalmitoyl-sn-glycero-3-phosphoethanolamine Copolymers and Their Micelles as a Drug Carrier. Journal of Applied Polymer Science 2010, 117 (1), 604-613.
18. Wang, T. W.; Jiang, M.; Wu, Y., Nanoparticles composed of PLGA and hyperbranched poly (amine-ester) as a drug carrier. Journal of Polymer Research 2010, 17 (3), 335-345.
19. Tan, J. J.; Cong, X. J.; Hu, L. M.; Wang, C. X.; Jia, L.; Liang, X. J., Therapeutic strategies underpinning the development of novel techniques for the treatment of HIV infection. Drug Discov. Today 2010, 15 (5-6), 186-197.
20. Miao, Q. H.; Xu, D. X.; Wang, Z.; Xu, L.; Wang, T. W.; Wu, Y.; Lovejoy, D. B.; Kalinowski, D. S.; Richardson, D. R.; Nie, G. J.; Zhao, Y. L., Amphiphilic hyper-branched co-polymer nanoparticles for the controlled delivery of anti-tumor agents. Biomaterials 2010, 31 (28), 7364-7375.
21. Meng, J.; Wang, D. L.; Wang, P. C.; Jia, L.; Chen, C.; Liang, X. J., Biomedical Activities of Endohedral Metallofullerene Optimized for Pharmaceutics. J. Nanosci. Nanotechnol. 2010, 10 (12), 8610-8616.
22. Ma, X.; Wang, D.; Wu, Y.; Ho, R. J. Y.; Jia, L.; Guo, P.; Hu, L.; Xing, G.; Zeng, Y.; Liang, X. J., AIDS treatment with novel anti-HIV compounds improved by nanotechnology. AAPS J. 2010, 12 (3), 272-278.
23. Ma, H. L.; Liang, X. J., Fullerenes as unique nanopharmaceuticals for disease treatment. Science China Chemistry 2010, 53 (11), 2233-2240.
24. Ma, H.; Wang, P. C.; Qian, F.; Liang, X. J., Biological Effects of Nanomaterials and Drugs Measured by the Small-animal SPECT/CT Imaging System IN VIVO. Acta Biophysica Sinica 2010, 26 ((8)), 691-701.
25. Liang, X. J.; Meng, H.; Wang, Y. Z.; He, H. Y.; Meng, J.; Lu, J.; Wang, P. C.; Zhao, Y. L.; Gao, X. Y.; Sun, B. Y.; Chen, C. Y.; Xing, G. M.; Shen, D. W.; Gottesman, M. M.; Wu, Y.; Yin, J. J.; Jia, L., Metallofullerene nanoparticles circumvent tumor resistance to cisplatin by reactivating endocytosis. Proc. Natl. Acad. Sci. USA 2010, 107 (16), 7449-7454.
26. Jiao, F.; Qu, Y.; Zhou, G. Q.; Liu, Y.; Li, W.; Ge, C. C.; Li, Y. F.; Hu, W.; Li, B.; Gao, Y. X.; Chen, C. Y., Modulation of Oxidative Stress by Functionalized Fullerene Materials in the Lung Tissues of Female C57/BL Mice with a Metastatic Lewis Lung Carcinoma. J. Nanosci. Nanotechnol. 2010, 10 (12), 8632-8637.
27. Jiao, F.; Liu, Y.; Qu, Y.; Li, W.; Zhou, G.; Ge, C. C.; Li, Y. F.; Sun, B. Y., Studies on anti-tumor and antimetastatic activities of fullerenol in a mouse breast cancer model. Carbon 2010, 48 (8), 2231-2243.
28. Guo, S. T.; Qiao, Y.; Wang, W.; He, H.; Deng, L.; Xing, J.; Xu, J.; Liang, X. J.; A., D., Poly(ε-caprolactone)-graft-poly(2-(N, N-dimethylamino) ethyl methacrylate) Nanoparticles: pH Dependent Thermo-Sensitive Multifunctional Carriers for Gene and Drug Delivery. Journal of Materials Chemistry 2010, 20, 6935-6941.
29. Zhang, Z. Y.; Zhao, Y. L.; Chai, Z. F., Applications of radiotracer techniques for the pharmacology and toxicology studies of nanomaterials. Chinese Science Bulletin 2009, 54 (2), 173-182.
30. Yin, J. J.; Lao, F.; Fu, P. P.; Wamer, W. G.; Zhao, Y. L.; Wang, P. C.; Qiu, Y.; Sun, B. Y.; Xing, G. M.; Dong, J. Q.; Liang, X. J.; Chen, C. Y., The scavenging of reactive oxygen species and the potential for cell protection by functionalized fullerene materials. Biomaterials 2009, 30 (4), 611-621.
31. Wu, Y.; Li, M. J.; Gao, H. X., Polymeric micelle composed of PLA and chitosan as a drug carrier. Journal of Polymer Research 2009, 16 (1), 11-18.
32. Wang, Y. Z.; Duan, X. L.; Li, Y. F.; Liang, X. J., Multidrug Resistance Mediated by Half ABC Transporter ABCG2. Progress in Biochemistry and Biophysics 2009, 36 (12), 1523-1529.
33. Wang, T. W.; Xu, Q.; Wu, Y.; Zeng, A. J.; Li, M. J.; Gao, H. X., Quaternized chitosan (QCS)/poly (aspartic acid) nanoparticles as a protein drug-delivery system. Carbohydrate Research 2009, 344 (7), 908-914.
34. Wang, P. C.; Blumenthal, R. P.; Zhao, Y. L.; Schneider, J. A.; Miller, N.; Grodzinski, P.; Gottesman, M. M.; Tinkle, S.; Wang, K.; Wang, C.; Liang, X. J., Building Scientific Progress without Borders: Nanobiology and Nanomedicine in China and the U.S. Cancer Research 2009, 69, 5294-5295.
35. Liu, Y.; Wang, B.; Wang, J. N.; Wan, W. Z.; Sun, R. H.; Zhao, Y. L.; Zhang, N., Down-regulation of PKC zeta expression inhibits chemotaxis signal transduction in human lung cancer cells. Lung Cancer 2009, 63 (2), 210-218.
36. Liu, Y.; Jiao, F.; Qiu, Y.; Li, W.; Qu, Y.; Tian, C. X.; Li, Y. F.; Bai, R.; Lao, F.; Zhao, Y. L.; Chai, Z. F.; Chen, C. Y., Immunostimulatory properties and enhanced TNF-alpha mediated cellular immunity for tumor therapy by C60(OH)20 nanoparticles. Nanotechnology 2009, 20 (41), 415102 (10pp).
37. Liu, Y.; Jiao, F.; Qiu, Y.; Li, W.; Lao, F.; Zhou, G. Q.; Sun, B. Y.; Xing, G. M.; Dong, J. Q.; Zhao, Y. L.; Chai, Z. F.; Chen, C. Y., The effect of Gd@C82(OH)22 nanoparticles on the release of Th1/Th2 cytokines and induction of TNF-alpha mediated cellular immunity. Biomaterials 2009, 30 (23-24), 3934-3945.
38. Jiang, M.; Wu, Y.; He, Y.; Nie, J., Micelles formed by self-assembly of hyperbranched poly (amine-ester)-co-(D,L-lactide) (HPAE-co-PLA) copolymers for protein drug delivery. Polymer International 2009, 58 (1), 31-39.
39. Jiang, M.; Wang, T. W.; Xu, Q.; Wu, Y., Novel Amphiphilic Hyperbranched Poly (amine-ester) Copolymers Nanoparticles as Protein Drug Delivery. Mini-Reviews in Medicinal Chemistry 2009, 9, 1342-1356.
40. Gottesman, M. M.; Hall, M. D.; Liang, X. J.; Shen, D. W., Resistance to Cisplatin Results from Multiple Mechanisms in Cancer Cells. In Platinum and Other Heavy Metal Compounds in Cancer Chemotherapy: Molecular Mechanisms and Clinical Applications, Bonetti, A.; Leone, R.; Muggia, F.; Howell, S. B., Eds. Humana Press: Totowa, New Jersey, 2009; pp 83-88.
41. Yin, J. J.; Lao, F.; Fu, P. P.; Wamer, W. G.; Zhao, Y. L.; Xing, G. M.; Gao, X. Y.; Sun, B. Y.; Li, X. Y.; Wang, P. C.; Chen, C. Y.; Liang, X. J., Inhibition of Tumor Growth by Endohedral Metallofullerenol Nanoparticles Optimized as Reactive Oxygen Species Scavenger. Molecular Pharmacology 2008, 74 (4), 1132-1140.
42. Liang, X. J.; Chen, C. Y.; Zhao, Y. L.; Jia, L.; Wang, P. C., Biopharmaceutics and Therapeutic Potential of Engineered Nanomaterials. Current Drug Metabolism 2008, 9, 697-709.
43. Chen, Z.; Chen, H.; Meng, H.; Xing, G. M.; Gao, X. Y.; Sun, B. Y.; Shi, X. L.; Yuan, H.; Zhang, C. C.; Liu, R.; Zhao, F.; Zhao, Y. L.; Fang, X. H., Bio-distribution and metabolic paths of silica coated CdSeS quantum dots. Toxicology and Applied Pharmacology 2008, 230 (3), 364-371.
44. Wang, J. X.; Chen, C. Y.; Li, B.; Yu, H. W.; Zhao, Y. L.; Sun, J.; Li, Y. F.; Xing, G. M.; Yuan, H.; Tang, J.; Chen, Z.; Meng, H.; Gao, Y. X.; Ye, C.; Chai, Z. F.; Zhu, C. F.; Ma, B. C.; Fang, X. H.; Wan, L. J., Antioxidative function and biodistribution of [Gd@C82(OH)22]n nanoparticles in tumor-bearing mice. Biochem. Pharmacol. 2006, 71 (6), 872-881.